Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models

• Main Authors: Po-Han Lin (Author), Yi-Fen Chiang (Author), Tzong-Ming Shieh (Author), Hsin-Yuan Chen (Author), Chun-Kuang Shih (Author), Tong-Hong Wang (Author), Kai-Lee Wang (Author), Tsui-Chin Huang (Author), Yong-Han Hong (Author), Sing-Chung Li (Author), Shih-Min Hsia (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patients with triple-negative breast cancer have few therapeutic strategy options. In this study, we investigated the effect of isoliquiritigenin (ISL) on the proliferation of triple-negative breast cancer cells. We found that treatment with ISL inhibited triple-negative breast cancer cell line (MDA...