Breakpoint characterization of a novel large intragenic deletion of <it>MUTYH </it>detected in a MAP patient: Case report

• Main Authors: de O Ferreira Fábio (Author), Santos Érika MM (Author), Krepischi Ana CV (Author), da Silva Felipe CC (Author), Torrezan Giovana T (Author), Rossi Benedito M (Author), Carraro Dirce M (Author)
• Format: Book
• Published: BMC, 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p><it>MUTYH</it>-associated polyposis (MAP) is a recessive, hereditary, colorectal cancer-predisposing syndrome caused by biallelic mutations in the <it>MUTYH </it>gene. Most <it>MUTYH </it>pathogeni...