Breakpoint characterization of a novel large intragenic deletion of <it>MUTYH </it>detected in a MAP patient: Case report

• Главные авторы: de O Ferreira Fábio (Автор), Santos Érika MM (Автор), Krepischi Ana CV (Автор), da Silva Felipe CC (Автор), Torrezan Giovana T (Автор), Rossi Benedito M (Автор), Carraro Dirce M (Автор)
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• Опубликовано: BMC, 2011-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p><it>MUTYH</it>-associated polyposis (MAP) is a recessive, hereditary, colorectal cancer-predisposing syndrome caused by biallelic mutations in the <it>MUTYH </it>gene. Most <it>MUTYH </it>pathogeni...