Functional Profiling of CFTR-Directed Therapeutics Using Pediatric Patient-Derived Nasal Epithelial Cell Models

• Main Authors: Jeffrey KiHyun Park (Author), Anura Shrivastava (Author), Chengkang Zhang (Author), Brian A. Pollok (Author), Walter E. Finkbeiner (Author), Elizabeth R. Gibb (Author), Ngoc P. Ly (Author), Beate Illek (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Functional profiling of CFTR-directed therapeutics offers the potential to provide significant benefits to young people with cystic fibrosis (CF). However, the development of 2D airway epithelial cell models for individual response tests in CF children remains a central task. The objective of this s...