Slc7a11 stimulates glutathione synthesis to preserve fatty acid metabolism in primary hepatocytes

• Main Authors: Yifan Liu (Author), Kaimin Wu (Author), Yinkun Fu (Author), Wenyan Li (Author), Xu-Yun Zhao (Author)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

ABSTRACTPrimary hepatocytes are widely used as a tool for studying metabolic function and regulation in the liver. However, the metabolic properties of primary hepatocytes are gradually lost after isolation. Here, we illustrated that fatty acid metabolism is the major compromised metabolic process i...