Lycopene Modulates THP1 and Caco2 Cells Inflammatory State through Transcriptional and Nontranscriptional Processes

• Main Authors: Njock Makon-Sébastien (Author), Fouchier Francis (Author), Seree Eric (Author), Villard Pierre Henri (Author), Landrier Jean François (Author), Pechere Laurent (Author), Barra Yves (Author), Champion Serge (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We revisited the action of a carotenoid, the lycopene, on the expression of proinflammatory genes, reactive oxygen species (ROS) production, and metalloprotease (MMP9) activity. THP1 and Caco2 cell lines were used as in vitro models for the two main cell types found in intestine tissue, that is, mon...