To elucidate the mechanism of "Scrophulariae Radix-Fritillaria" in goiter by integrated metabolomics and serum pharmaco-chemistry

• Những tác giả chính: Lixin Chen (Tác giả), Wei Liang (Tác giả), Kun Zhang (Tác giả), Zishuo Wang (Tác giả), Wei Cheng (Tác giả), Wenlan Li (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

The pharmacodynamic substances in "Scrophulariae Radix-Fritillaria" and the molecular mechanisms underlying its therapeutic effects against goiter were analyzed through metabolomics and serum pharmaco-chemistry. A rat model of goiter was established using propylthiouracil (PTU), and the an...