Combined hyperforin and lanicemine treatment instead of ketamine or imipramine restores behavioral deficits induced by chronic restraint stress and dietary zinc restriction in mice

• Main Authors: Bartłomiej Pochwat (Author), Paulina Misztak (Author), Julia Masternak (Author), Ewa Bączyńska (Author), Krystian Bijata (Author), Matylda Roszkowska (Author), Monika Bijata (Author), Jakub Włodarczyk (Author), Małgorzata Szafarz (Author), Elżbieta Wyska (Author), Bożena Muszyńska (Author), Agata Krakowska (Author), Włodzimierz Opoka (Author), Gabriel Nowak (Author), Bernadeta Szewczyk (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinical and preclinical studies show evidence that chronic stress or nutritional deficits in dietary zinc (Zn) intake may be risk factors for developing major depressive disorder (MDD). Furthermore, there may be possible links between low serum Zn levels and development of treatment-resistant depre...