The Future of Tissue-Targeted Lipid Nanoparticle-Mediated Nucleic Acid Delivery

The earliest example of in vivo expression of exogenous mRNA is by direct intramuscular injection in mice without the aid of a delivery vehicle. The current state of the art for therapeutic nucleic acid delivery is lipid nanoparticles (LNP), which are composed of cholesterol, a helper lipid, a PEGyl...

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Main Authors: Ruvanthi N. Kularatne (Author), Rachael M. Crist (Author), Stephan T. Stern (Author)
Format: Book
Published: MDPI AG, 2022-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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