The Future of Tissue-Targeted Lipid Nanoparticle-Mediated Nucleic Acid Delivery
The earliest example of in vivo expression of exogenous mRNA is by direct intramuscular injection in mice without the aid of a delivery vehicle. The current state of the art for therapeutic nucleic acid delivery is lipid nanoparticles (LNP), which are composed of cholesterol, a helper lipid, a PEGyl...
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MDPI AG,
2022-07-01T00:00:00Z.
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