siRNA Versus miRNA as Therapeutics for Gene Silencing

• Main Authors: Jenny K W Lam (Author), Michael Y T Chow (Author), Yu Zhang (Author), Susan W S Leung (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Discovered a little over two decades ago, small interfering RNAs (siRNAs) and microRNAs (miRNAs) are noncoding RNAs with important roles in gene regulation. They have recently been investigated as novel classes of therapeutic agents for the treatment of a wide range of disorders including cancers an...