Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa

Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We so...

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Main Authors: Laura E. Pugh (Author), Jacob S. Roberts (Author), Nikita Viswasam (Author), Elizabeth Hahn (Author), Sophia Ryan (Author), Ghilane Turpin (Author), Carrie E. Lyons (Author), Stefan Baral (Author), Bhakti Hansoti (Author)
Format: Book
Published: Elsevier, 2022-10-01T00:00:00Z.
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Summary:Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We sought to complete a systematic review to comprehensively examine ART adherence and retention in care interventions in Sub-Saharan Africa and to report on the implementation of interventions in real-world settings to inform future health investments in HIV care. Interventions were grouped according to their impact on individual, community, and health-systems levels. While a vast majority of studies evaluated a combination of interventions, those studies that incorporated the community as a resource were most successful. In addition, providing education and behavior reminders proved effective and should be accompanied by community and peer efforts for best results. Multi-level interventions, such as combining individual and community-level interventions showed promising results for long term ART adherence.
Item Description:1876-0341
10.1016/j.jiph.2022.08.012