Scabies mite peritrophins are potential targets of human host innate immunity.

• Main Authors: Angela Mika (Author), Priscilla Goh (Author), Deborah C Holt (Author), Dave J Kemp (Author), Katja Fischer (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Pruritic scabies lesions caused by Sarcoptes scabiei burrowing in the stratum corneum of human skin facilitate opportunistic bacterial infections. Emerging resistance to current therapeutics emphasizes the need to identify novel targets for protective intervention. We have characterized...