Gypenoside induces apoptosis by inhibiting the PI3K/AKT/mTOR pathway and enhances T-cell antitumor immunity by inhibiting PD-L1 in gastric cancer

• Egile Nagusiak: Hongliang Wu (Egilea), Wenjing Lai (Egilea), Qiaoling Wang (Egilea), Qiang Zhou (Egilea), Rong Zhang (Egilea), Yu Zhao (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Introduction: Gypenoside is a natural extract of Gynostemma pentaphyllum (Thunb.) Makino, a plant in the Cucurbitaceae family. It has been reported to have antitumor effects on the proliferation, migration and apoptosis of various types of cancer cells. However, the use of gypenoside in the treatmen...