Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice

• Main Authors: Malavika Deodhar (Author), Sweilem B Al Rihani (Author), Meghan J. Arwood (Author), Lucy Darakjian (Author), Pamela Dow (Author), Jacques Turgeon (Author), Veronique Michaud (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In an ageing society, polypharmacy has become a major public health and economic issue. Overuse of medications, especially in patients with chronic diseases, carries major health risks. One common consequence of polypharmacy is the increased emergence of adverse drug events, mainly from drug-drug in...