Solubility enhancement of carvedilol by multicomponent crystal approach using glycine and arginine as coformers

A Carvedilol is a member of BCS class II, it has a low solubility and bioavailability. This work intends to increase the solubility of carvedilol using a multicomponent crystal method. Based on in silico investigations showed that carvedilol-arginine formed one hydrogen bond and carvedilol-glycine f...

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Main Authors: Iyan Sopyan (Author), Wuri Ariestika Sari (Author), Sandra Megantara (Author), Taofik Rusdiana (Author)
Format: Book
Published: Pensoft Publishers, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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