Monoclonal Antibody Functionalized, and L-lysine α-Oxidase Loaded PEGylated-Chitosan Nanoparticle for HER2/Neu Targeted Breast Cancer Therapy

Monoclonal Antibody Functionalized, and L-lysine α-Oxidase Loaded PEGylated-Chitosan Nanoparticle for HER2/Neu Targeted Breast Cancer Therapy

Herein, we designed a nanocarrier to deliver the LO specifically to HER2+ breast cancer (BC) cells, where functionalization of mAb (anti-HER2+) with PEGylated chitosan enabled it to target the HER2+ BC cells. Taking advantage of overexpression of HER2+ in cancer cells, our nanocarrier (CS-LO-PEG-HER...

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Main Authors: Kandasamy Saravanakumar (Author), Anbazhagan Sathiyaseelan (Author), Soyoung Park (Author), Song-Rae Kim (Author), Veeraraghavan Vishnu Priya (Author), Myeong-Hyeon Wang (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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