Antitumor effects of iridomyrmecin in HeLa cervical cancer cells are mediated via apoptosis induction, loss of mitochondrial membrane potential, cell cycle arrest and down-regulation of PI3K/Akt and up-regulation of lncRNA CCAT2 expression

• Main Authors: Li Lin (Author), Xiao-Ling Cheng (Author), Ming-Zhe Li (Author), Tao Wang (Author), Min-Hai Dong (Author), Zhen-Yu Wang (Author), Min Liao (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The main purpose of the current study was to study the antitumor effects of iridomyrmecin against human cervical cancer cells (HeLa). Its effects on apoptosis induction, cell cycle phase distribution, PI3K/Akt signalling pathway and long non-coding RNA (lncRNA) were also investigated. Cytotoxic effe...