The Bone Morphogenetic Protein Signaling Inhibitor LDN-193189 Enhances Metastasis Development in Mice

The Bone Morphogenetic Protein Signaling Inhibitor LDN-193189 Enhances Metastasis Development in Mice

Breast cancer with bone metastasis is essentially incurable with current anticancer therapies. The bone morphogenetic protein (BMP) pathway is an attractive therapeutic candidate, as it is involved in the bone turnover and in cancer cell formation and their colonization of distant organs such as the...

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Main Authors: Julien Vollaire (Author), Irma Machuca-Gayet (Author), Jonathan Lavaud (Author), Aurélie Bellanger (Author), Lamia Bouazza (Author), Soumaya El Moghrabi (Author), Isabelle Treilleux (Author), Jean-Luc Coll (Author), Olivier Peyruchaud (Author), Véronique Josserand (Author), Pascale A. Cohen (Author)
Format: Book
Published: Frontiers Media S.A., 2019-06-01T00:00:00Z.
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