Small-volume in vitro lipid digestion measurements for assessing drug dissolution in lipid-based formulations using SAXS

• Main Authors: Nafia F. Khan (Author), Malinda Salim (Author), Syaza Y. Binte Abu Bakar (Author), Kurt Ristroph (Author), Robert K. Prud'homme (Author), Adrian Hawley (Author), Ben J. Boyd (Author), Andrew J. Clulow (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipid-based formulations improve the absorption capacity of poorly-water-soluble drugs and digestion of the formulation is a critical step in that absorption process. A recent approach to understanding the propensity for drug to dissolve in digesting lipid-based formulations couples an in vitro pH-s...