The Ability of Some Polysaccharides to Disaggregate Lysozyme Amyloid Fibrils and Renature the Protein

• Main Authors: Olga Makshakova (Author), Liliya Bogdanova (Author), Dzhigangir Faizullin (Author), Diliara Khaibrakhmanova (Author), Sufia Ziganshina (Author), Elena Ermakova (Author), Yuriy Zuev (Author), Igor Sedov (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The deposition of proteins in the form of insoluble amyloid fibril aggregates is linked to a range of diseases. The supramolecular architecture of such deposits is governed by the propagation of β-strands in the direction of protofilament growth. In the present study, we analyze the structural chang...