Challenges in Permeability Assessment for Oral Drug Product Development

• Main Authors: Mirko Koziolek (Author), Patrick Augustijns (Author), Constantin Berger (Author), Rodrigo Cristofoletti (Author), David Dahlgren (Author), Janneke Keemink (Author), Pär Matsson (Author), Fiona McCartney (Author), Marco Metzger (Author), Mario Mezler (Author), Janis Niessen (Author), James E. Polli (Author), Maria Vertzoni (Author), Werner Weitschies (Author), Jennifer Dressman (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2023-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Drug permeation across the intestinal epithelium is a prerequisite for successful oral drug delivery. The increased interest in oral administration of peptides, as well as poorly soluble and poorly permeable compounds such as drugs for targeted protein degradation, have made permeability a key param...