Anti-inflammatory therapy of atherosclerosis: focusing on IKKβ

• Main Authors: Jiali Gan (Author), Lin Guo (Author), Xiaolu Zhang (Author), Qun Yu (Author), Qiuyue Yang (Author), Yilin Zhang (Author), Wenyun Zeng (Author), Xijuan Jiang (Author), Maojuan Guo (Author)
• Format: Book
• Published: BMC, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Chronic low-grade inflammation has been identified as a major contributor in the development of atherosclerosis. Nuclear Factor-κappa B (NF-κB) is a critical transcription factors family of the inflammatory pathway. As a major catalytic subunit of the IKK complex, IκB kinase β (IKKβ) drives...