Host predisposition by endogenous Transforming Growth Factor-β1 overexpression promotes pulmonary fibrosis following bleomycin injury

• Main Authors: Ferguson Mark WJ (Author), Martin Gail (Author), Tomlinson Annette (Author), Birch Mary (Author), Keating Dominic T (Author), Malizia Andrea P (Author), Haider Yussef (Author), Doran Peter P (Author), Egan Jim J (Author)
• Format: Book
• Published: BMC, 2007-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Idiopathic Pulmonary Fibrosis (IPF) is a progressive diffuse disease involving the lung parenchyma. Despite recent advances, the molecular mechanisms of the initiation and progression of this disease remain elusive. Previous studies...