Exploration of 2D and 3D-QSAR analysis and docking studies for novel dihydropteridone derivatives as promising therapeutic agents targeting glioblastoma

Background: Dihydropteridone derivatives represent a novel class of PLK1 inhibitors, exhibiting promising anticancer activity and potential as chemotherapeutic drugs for glioblastoma.Objective: The aim of this study is to develop 2D and 3D-QSAR models to validate the anticancer activity of dihydropt...

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Main Authors: Meichen Pan (Author), Lingxue Cheng (Author), Yiguo Wang (Author), Chunyi Lyu (Author), Chao Hou (Author), Qiming Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
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