Schaftoside ameliorates oxygen glucose deprivation-induced inflammation associated with the TLR4/Myd88/Drp1-related mitochondrial fission in BV2 microglia cells

• Main Authors: Kecheng Zhou (Author), Jiayu Wu (Author), Jie Chen (Author), Ye Zhou (Author), Xiaolong Chen (Author), Qiaoyun Wu (Author), Yangxinzi Xu (Author), Wenzhan Tu (Author), Xinfa Lou (Author), Guanhu Yang (Author), Songhe Jiang (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Neuroinflammation plays a major role in the development of ischemic stroke, and regulation of the proinflammatory TLR4 signaling pathway in microglia stands to be a promising therapeutic strategy for stroke intervention. Recently, the homeostasis of mitochondrial dynamics has also been r...