Osteopontin Overexpression Induced Tumor Progression and Chemoresistance to Oxaliplatin through Induction of Stem-Like Properties in Human Colorectal Cancer

• Main Authors: Lui Ng (Author), Timothy Wan (Author), Ariel Chow (Author), Deepak Iyer (Author), Johnny Man (Author), Guanghua Chen (Author), Thomas Chung-Cheung Yau (Author), Oswens Lo (Author), Chi-Chung Foo (Author), Jensen Tung-Chung Poon (Author), Ronnie Tung-Ping Poon (Author), Roberta Pang (Author), Wai-Lun Law (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colorectal cancer (CRC) is one of the most common and fatal malignancies worldwide. The poor prognosis of colorectal cancer patients is due to development of chemoresistance and cancer metastasis. Recently osteopontin (OPN) has been associated with stem-like properties in colorectal cancer. This stu...