Sabatolimab (MBG453) model‐informed drug development for dose selection in patients with myelodysplastic syndrome/acute myeloid leukemia and solid tumors

Abstract Sabatolimab is a novel immunotherapy with immuno‐myeloid activity that targets T‐cell immunoglobulin domain and mucin domain‐3 (TIM‐3) on immune cells and leukemic blasts. It is being evaluated for the treatment of myeloid malignancies in the STIMULUS clinical trial program. The objective o...

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Main Authors: Siyan Xu (Author), Na Zhang (Author), Mikael L. Rinne (Author), Haiying Sun (Author), Andrew M. Stein (Author)
Format: Book
Published: Wiley, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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