Naltrexone Protects Against Lipopolysaccharide/D-Galactosamine-Induced Hepatitis in Mice

• Main Authors: Chien-Chuan Wang (Author), Pao-Yun Cheng (Author), Yie-Jen Peng (Author), Edwin SC Wu (Author), Hsiao-Ping Wei (Author), Mao-Hsiung Yen (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Naltrexone, an opioid receptor antagonist, has been claimed to have anti-inflammatory and immunomodulatory effects both in vitro and in vivo. Thus, the aim of this study was to evaluate the effects of naltrexone on acute hepatitis induced by intraperitoneal (i.p.) administration of lipopolysaccharid...