In Vivo Evaluation of ⁶⁸Ga-Labeled NOTA-EGFRvIII Aptamer in EGFRvIII-Positive Glioblastoma Xenografted Model

• Main Authors: Jun Young Park (Author), Ye Lim Cho (Author), Tae Sup Lee (Author), Daekyun Lee (Author), Ju-Hyung Kang (Author), Soryong Lim (Author), Yujin Lee (Author), Jae Hyun Lim (Author), Won Jun Kang (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

EGFRvIII is expressed only in tumor cells and strongly in glioblastoma and is considered a promising target in cancer diagnosis and therapy. Aptamers are synthetic single-stranded oligonucleotides that bind to biochemical target molecules with high binding affinity and specificity. This study examin...