Mitochondrial GWAS and association of nuclear - mitochondrial epistasis with BMI in T1DM patients

• Main Authors: Agnieszka H. Ludwig-Słomczyńska (Author), Michał T. Seweryn (Author), Przemysław Kapusta (Author), Ewelina Pitera (Author), Samuel K. Handelman (Author), Urszula Mantaj (Author), Katarzyna Cyganek (Author), Paweł Gutaj (Author), Łucja Dobrucka (Author), Ewa Wender-Ożegowska (Author), Maciej T. Małecki (Author), Paweł P. Wołkow (Author)
• Format: Book
• Published: BMC, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background BMI is a strong indicator of complications from type I diabetes, especially under intensive treatment. Methods We have genotyped 435 type 1 diabetics using Illumina Infinium Omni Express Exome-8 v1.4 arrays and performed mitoGWAS on BMI. We identified additive interactions betwee...