Mitochondrial GWAS and association of nuclear - mitochondrial epistasis with BMI in T1DM patients

• Glavni autori: Agnieszka H. Ludwig-Słomczyńska (Autor), Michał T. Seweryn (Autor), Przemysław Kapusta (Autor), Ewelina Pitera (Autor), Samuel K. Handelman (Autor), Urszula Mantaj (Autor), Katarzyna Cyganek (Autor), Paweł Gutaj (Autor), Łucja Dobrucka (Autor), Ewa Wender-Ożegowska (Autor), Maciej T. Małecki (Autor), Paweł P. Wołkow (Autor)
• Format: Knjiga
• Izdano: BMC, 2020-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background BMI is a strong indicator of complications from type I diabetes, especially under intensive treatment. Methods We have genotyped 435 type 1 diabetics using Illumina Infinium Omni Express Exome-8 v1.4 arrays and performed mitoGWAS on BMI. We identified additive interactions betwee...