Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials
Photodynamic therapy (PDT) is an emerging, non-invasive therapeutic strategy that involves photosensitizer (PS) drugs and external light for the treatment of diseases. Despite the great progress in PS-mediated PDT, their clinical applications are still hampered by poor water solubility and tissue/ce...
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| Format: | Book |
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Elsevier,
2016-07-01T00:00:00Z.
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| 001 | doaj_b3ddf6c9f1ae4e9c94b5d1df7f1d5b17 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Eun Ji Hong |e author |
| 700 | 1 | 0 | |a Dae Gun Choi |e author |
| 700 | 1 | 0 | |a Min Suk Shim |e author |
| 245 | 0 | 0 | |a Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials |
| 260 | |b Elsevier, |c 2016-07-01T00:00:00Z. | ||
| 500 | |a 2211-3835 | ||
| 500 | |a 2211-3843 | ||
| 500 | |a 10.1016/j.apsb.2016.01.007 | ||
| 520 | |a Photodynamic therapy (PDT) is an emerging, non-invasive therapeutic strategy that involves photosensitizer (PS) drugs and external light for the treatment of diseases. Despite the great progress in PS-mediated PDT, their clinical applications are still hampered by poor water solubility and tissue/cell specificity of conventional PS drugs. Therefore, great efforts have been made towards the development of nanomaterials that can tackle fundamental challenges in conventional PS drug-mediated PDT for cancer treatment. This review highlights recent advances in the development of nano-platforms, in which various functionalized organic and inorganic nanomaterials are integrated with PS drugs, for significantly enhanced efficacy and tumor-selectivity of PDT. | ||
| 546 | |a EN | ||
| 690 | |a Organic nanomaterials | ||
| 690 | |a Inorganic nanomaterials | ||
| 690 | |a Nanoparticles | ||
| 690 | |a Photodynamic therapy | ||
| 690 | |a Photosensitizer | ||
| 690 | |a Targeted therapy | ||
| 690 | |a Cancer therapy | ||
| 690 | |a Near-infrared light | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Acta Pharmaceutica Sinica B, Vol 6, Iss 4, Pp 297-307 (2016) | |
| 787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S2211383515300915 | |
| 787 | 0 | |n https://doaj.org/toc/2211-3835 | |
| 787 | 0 | |n https://doaj.org/toc/2211-3843 | |
| 856 | 4 | 1 | |u https://doaj.org/article/b3ddf6c9f1ae4e9c94b5d1df7f1d5b17 |z Connect to this object online. |