Exploring Light-Sensitive Nanocarriers for Simultaneous Triggered Antibiotic Release and Disruption of Biofilms Upon Generation of Laser-Induced Vapor Nanobubbles

• Main Authors: Eline Teirlinck (Author), Alexandre Barras (Author), Jing Liu (Author), Juan C. Fraire (Author), Tatu Lajunen (Author), Ranhua Xiong (Author), Katrien Forier (Author), Chengnan Li (Author), Arto Urtti (Author), Rabah Boukherroub (Author), Sabine Szunerits (Author), Stefaan C. De Smedt (Author), Tom Coenye (Author), Kevin Braeckmans (Author)
• Format: Book
• Published: MDPI AG, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Impaired penetration of antibiotics through bacterial biofilms is one of the reasons for failure of antimicrobial therapy. Hindered drug diffusion is caused on the one hand by interactions with the sticky biofilm matrix and on the other hand by the fact that bacterial cells are organized in densely...