Toll-Like Receptor Signaling Pathways-Therapeutic Opportunities
Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of multiple inflammatory genes, which then play a protective role against infection. However, aberrant activation of TLR signaling has a significant...
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Hindawi Limited,
2010-01-01T00:00:00Z.
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A1234.567 |
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