Inflammatory Alterations to Renal Lymphatic Endothelial Cell Gene Expression in Mouse Models of Hypertension

• Main Authors: Justin G. McDermott (Author), Bethany L. Goodlett (Author), Heidi A. Creed (Author), Shobana Navaneethabalakrishnan (Author), Joseph M. Rutkowski (Author), Brett M. Mitchell (Author)
• Format: Book
• Published: Karger Publishers, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Hypertension (HTN) is a major cardiovascular disease that can cause and be worsened by renal damage and inflammation. We previously reported that renal lymphatic endothelial cells (LECs) increase in response to HTN and that augmenting lymphangiogenesis in the kidneys reduces blood pres...