Inside the Mechanism of Action of Three Pyrazole Derivatives in Human Platelets and Endothelial Cells

• Main Authors: Chiara Brullo (Author), Eleonora Russo (Author), Silvano Garibaldi (Author), Paola Altieri (Author), Pietro Ameri (Author), Silvia Ravera (Author), Maria Grazia Signorello (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the effort to obtain multitarget compound interfering with inflammation, oxidative stress, and tumorigenesis, we synthesized a small library of pyrazole compounds, selecting <b>4a</b>, <b>4f</b>, and <b>4g</b> as the most noteworthy being IC<sub>50</su...