Physicochemical properties determining drug detection in skin

• Hauptverfasser: Wout Bittremieux (Verfasst von), Rohit S. Advani (Verfasst von), Alan K. Jarmusch (Verfasst von), Shaden Aguirre (Verfasst von), Aileen Lu (Verfasst von), Pieter C. Dorrestein (Verfasst von), Shirley M. Tsunoda (Verfasst von)
• Format: Buch
• Veröffentlicht: Wiley, 2022-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Chemicals, including some systemically administered xenobiotics and their biotransformations, can be detected noninvasively using skin swabs and untargeted metabolomics analysis. We sought to understand the principal drivers that determine whether a drug taken orally or systemically is like...