The Addition of EGFR Inhibitors in Neoadjuvant Therapy for KRAS-Wild Type Locally Advanced Rectal Cancer Patients: A Systematic Review and Meta-Analysis

• Main Authors: Xi Zhong (Author), Yue Zhou (Author), Wanbin Cui (Author), Xin Su (Author), Zhexu Guo (Author), Iko Hidasa (Author), Qincai Li (Author), Zhenning Wang (Author), Yongxi Song (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundPatients with locally advanced rectal cancer (LARC) are at higher risk of local and distant recurrence and are thus more vulnerable to metastatic diseases. Neoadjuvant chemoradiotherapy (nCRT) and subsequent curative resection with total mesorectal excision (TME) followed by adjuvant chemo...