Bioequivalence evaluation and food effect assessment of Lisinopril/amlodipine tablets in healthy Chinese subjects under fasting and fed conditions

• Main Authors: Ting Li (Author), Yan-ping Liu (Author), Shu-qin Liu (Author), Ping Shi (Author), Xin Jiang (Author), Ye Tao (Author), Xiao-meng Gao (Author), Ya-ping Ma (Author), Yu Cao (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Purpose The combination of lisinopril and amlodipine has a marked additional effect on blood pressure and fewer side effects than individual monotherapy. This study was conducted to compare the pharmacokinetic parameters and evaluate the bioequivalence between two Lisinopril/amlodipine tabl...