Altered Cytokine Endotoxin Responses in Neonatal Encephalopathy Predict MRI Outcomes

• Main Authors: Mary Isabel O'Dea (Author), Lynne A. Kelly (Author), Ellen McKenna (Author), Tammy Strickland (Author), Tim P. Hurley (Author), John Butler (Author), Claudine Vavasseur (Author), Afif F. EL-Khuffash (Author), Jan Miletin (Author), Lida Fallah (Author), Arthur White (Author), Jason Wyse (Author), Eleanor J. Molloy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Neonatal encephalopathy (NE) is associated with adverse neurodevelopmental outcome and is linked with systemic inflammation. Pro-inflammatory and anti-inflammatory cytokines are known to play a role in the pathology of NE by activating innate immune cells.Methods: Eighty-seven infants we...