Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits

Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits

Abstract Clinical response of clozapine is closely associated with serum concentration. Although tobacco smoking is the key environmental factor underlying interindividual variability in clozapine metabolism, recent genome‐wide studies suggest that CYP1A and NFIB genetic variants may also be of sign...

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Main Authors: Hasan Çağın Lenk (Author), Robert Løvsletten Smith (Author), Kevin S. O'Connell (Author), Marin M. Jukić (Author), Marianne Kristiansen Kringen (Author), Ole A. Andreassen (Author), Magnus Ingelman‐Sundberg (Author), Espen Molden (Author)
Format: Book
Published: Wiley, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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