Radiofrequency Combined with Intratumoral Immunotherapy: Preclinical Results and Safety in Metastatic Colorectal Carcinoma

• Main Authors: Johanne Seguin (Author), Mostafa El Hajjam (Author), Josette Legagneux (Author), Sarah Diakhaby (Author), Nathalie Mignet (Author), Vincent Boudy (Author), Balthazar Toussaint (Author), Frederique Peschaud (Author), Jean François Emile (Author), Claude Capron (Author), Robert Malafosse (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiofrequency ablation (RFA) of cancer induces an anti-tumor immunity, which is insufficient to prevent recurrences. In mice, RFA-intratumoral immunotherapy by granulocyte-macrophage colony-stimulating factor (GM-CSF) and Bacillus Calmette-Guerin resulted in complete metastases regression. Infectio...