Formyl peptide receptor type 2 (FPR2) deficiency in myeloid cells amplifies sepsis-induced cardiac dysfunction

Formyl peptide receptor type 2 (FPR2) deficiency in myeloid cells amplifies sepsis-induced cardiac dysfunction

Using a global formyl-peptide receptor (Fpr)2 knockout mouse colony, we have reported the modulatory properties of this pro-resolving receptor in polymicrobial sepsis. Herein, we have used a humanized FPR2 (hFPR2) mouse colony bearing an intact or a selective receptor deficiency in myeloid cells to...

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Main Authors: Jianmin Chen (Author), Shani Austin-Williams (Author), Caroline Elizabeth O'Riordan (Author), Pol Claria-Ribas (Author), Michelle A Sugimoto (Author), Lucy V Norling (Author), Christoph Thiemermann (Author), Mauro Perretti (Author)
Format: Book
Published: Karger Publishers, 2023-04-01T00:00:00Z.
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