Optimized functional and structural design of dual-target LMRAP, a bifunctional fusion protein with a 25-amino-acid antitumor peptide and GnRH Fc fragment

To develop fusion protein of a GnRH Fc fragment and the integrin targeting AP25 antitumor peptide for GnRH receptor-expressing cancer therapy. The LMRAP fusion protein was constructed. A transwell invasion assay was performed. The gene mRNA and protein levels of GnRHR-I, α5β1, and αvβ3 in different...

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Main Authors: Meng Li (Author), Hanmei Xu (Author), Junzhi Wang (Author)
Format: Book
Published: Elsevier, 2020-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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