New 3-O-substituted xanthone derivatives as promising acetylcholinesterase inhibitors

• Main Authors: Zi Han Loh (Author), Huey Chong Kwong (Author), Kok Wai Lam (Author), Soek Sin Teh (Author), Gwendoline Cheng Lian Ee (Author), Ching Kheng Quah (Author), Anthony Siong Hock Ho (Author), Siau Hui Mah (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new series of 3-O-substituted xanthone derivatives were synthesised and evaluated for their anti-cholinergic activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The results indicated that the xanthone derivatives possessed good AChE inhibitory activity with eleven of t...