Freezing Weakens the Barrier Function of Reconstructed Human Epidermis as Evidenced by Raman Spectroscopy and Percutaneous Permeation

• Main Authors: Yuri Dancik (Author), Hichem Kichou (Author), Christophe Eklouh-Molinier (Author), Martin Soucé (Author), Emilie Munnier (Author), Igor Chourpa (Author), Franck Bonnier (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development and characterization of reconstructed human epidermis (RHE) is an active area of R&D. RHE can replace animal tissues in pharmaceutical, toxicological and cosmetic sciences, yielding scientific and ethical advantages. RHEs remain costly, however, due to consumables and time requir...