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Preparation of Hot-Melt-Extruded Solid Dispersion Based on Pre-Formulation Strategies and Its Enhanced Therapeutic Efficacy

In this study, an amorphous solid dispersion containing the poorly water-soluble drug, bisacodyl, was prepared by hot-melt extrusion to enhance its therapeutic efficacy. First, the miscibility and interaction between the drug and polymer were investigated as pre-formulation strategies using various...

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Main Authors:	Seon-Kwang Lee (Author), Eun-Sol Ha (Author), Heejun Park (Author), Kyu-Tae Kang (Author), Ji-Su Jeong (Author), Jeong-Soo Kim (Author), In-hwan Baek (Author), Min-Soo Kim (Author)
Format:	Book
Published:	MDPI AG, 2023-11-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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