Design, Synthesis and In Vitro Biological Activity of Novel C-7 Methylene Congeners of Furanoallocolchicinoids

A series of novel heterocyclic colchicine derivatives bearing a C-7 methylene fragment were synthesized via Wittig, Horner-Wadsworth-Emmons and Nenajdenko-Shastin olefination approaches. The in vitro biological activities of the most promising compounds were investigated using MTT assays and cell cy...

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Main Authors: Iuliia A. Gracheva (Author), Elena V. Svirshchevskaya (Author), Ekaterina S. Shchegravina (Author), Yulia B. Malysheva (Author), Alsu R. Sitdikova (Author), Alexey Yu. Fedorov (Author)
Format: Book
Published: MDPI AG, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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