Bioactive Polyphenols from Pomegranate Juice Reduce 5-Fluorouracil-Induced Intestinal Mucositis in Intestinal Epithelial Cells

• Main Authors: Giacomo Pepe (Author), Shara Francesca Rapa (Author), Emanuela Salviati (Author), Alessia Bertamino (Author), Giulia Auriemma (Author), Stella Cascioferro (Author), Giuseppina Autore (Author), Andrea Quaroni (Author), Pietro Campiglia (Author), Stefania Marzocco (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intestinal epithelial cells (IECs) play a pivotal role in maintaining intestinal homeostasis. Different noxious agents, among them also anticancer therapies, can impair intestinal epithelial integrity triggering inflammation and oxidative stress. A frequent complication of chemotherapy is gastrointe...