A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes

• Main Authors: Pascal Gottmann (Author), Meriem Ouni (Author), Sophie Saussenthaler (Author), Julian Roos (Author), Laura Stirm (Author), Markus Jähnert (Author), Anne Kamitz (Author), Nicole Hallahan (Author), Wenke Jonas (Author), Andreas Fritsche (Author), Hans-Ulrich Häring (Author), Harald Staiger (Author), Matthias Blüher (Author), Pamela Fischer-Posovszky (Author), Heike Vogel (Author), Annette Schürmann (Author)
• Format: Book
• Published: Elsevier, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Obesity and type 2 diabetes (T2D) arise from the interplay between genetic, epigenetic, and environmental factors. The aim of this study was to combine bioinformatics and functional studies to identify miRNAs that contribute to obesity and T2D. Methods: A computational framework (miR-QTL-...