Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model

• Váldodahkkit: Juan Sebastian Yakisich (Dahkki), Neelam Azad (Dahkki), Rajkumar Venkatadri (Dahkki), Yogesh Kulkarni (Dahkki), Clayton Wright (Dahkki), Vivek Kaushik (Dahkki), Anand Krishnan V. Iyer (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2016-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Like with most solid tumors, the presence of a subpopulation of cancer stem cells (CSCs) or cancer stem-like cells (CS-LCs) has been associated with chemoresistance and tumor relapse in lung cancer cells. In the absence of serum, CSCs/CS-LCs have the ability to grow as lung tumorspheres (LTSs), and...