Functional differences between protamine preparations for the transfection of mRNA

• Main Authors: Natalia Teresa Jarzebska (Author), Severin Lauchli (Author), Christoph Iselin (Author), Lars E French (Author), Pal Johansen (Author), Emmanuella Guenova (Author), Thomas M Kündig (Author), Steve Pascolo (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protamine is a natural cationic peptide mixture used as a drug for the neutralization of heparin and in formulations of slow-release insulin. In addition, Protamine can be used for the stabilization and delivery of nucleic acids (antisense, small interfering RNA (siRNA), immunostimulatory nucleic ac...